AMPK activator
AICAR reconstitution calculator
AICAR is commonly supplied as 50 mg vials. Pick a vial size and a water volume to see the concentration and what each syringe mark holds. Enter a target amount to see the draw. This page does not suggest any amount.
Work backwards: pick how many syringe units you want each draw to be, and the calculator tells you how much water gives that concentration.
Example values shown. Larger draws (10 units or more) are easier to measure accurately than very small ones.
Estimate how long a vial lasts and what a protocol costs, from your own price and schedule.
Example values shown. Replace them with your own.
Draw to
– units
– mL on a U-100 syringe
- Concentration
- – mg/mL
- Per 1 unit
- – mcg
- Draws per vial
- –
- Total in vial
- – mcg
What each mark on the syringe holds
| Units | mL | Contains |
|---|
Add
– mL
of bacteriostatic water
- Concentration
- – mg/mL
- Draws per vial
- –
Per 30 days
$–
- Cost per use
- $–
- Uses per vial
- –
- One vial lasts
- – days
- Vials per 30 days
- –
Assumes no loss to dead space in the syringe or vial. Real-world usage is usually a few percent higher.
About AICAR
AICAR is a nucleoside that cells convert into an AMP mimic, activating AMP-activated protein kinase (AMPK), the cell’s energy sensor. In a 2008 study, sedentary mice given AICAR for four weeks ran 44% farther, which led to its description as an exercise mimetic and its ban in sport.
AICAR calculator questions
How much bacteriostatic water do I add to a 50 mg AICAR vial?
The calculator does not prescribe a volume; the right choice depends on how large you want each draw to be. As arithmetic: 50 mg in 5 mL gives 10 mg/mL, so each unit on a U-100 syringe holds 100 mcg. Use the “Water to add” tab to work backwards from a draw size.
What concentration does AICAR have after reconstitution?
Concentration is the vial mass divided by the water volume. For example, 50 mg in 5 mL is 10 mg/mL. Check the certificate of analysis for net peptide content, which is usually lower than the label.
Where can I read the research on AICAR?
See the AICAR research profile for mechanism, study findings, safety and regulatory status, with references.