GIP, GLP-1 and glucagon receptor agonist

Retatrutide reconstitution calculator

Retatrutide is commonly supplied as 5 mg, 10 mg, 12 mg, 15 mg, 20 mg, 30 mg vials. Pick a vial size and a water volume to see the concentration and what each syringe mark holds. Enter a target amount to see the draw. This page does not suggest any amount.

Vial contents
Diluent
Target amount per draw
Syringe

Draw to

– units

– mL on a U-100 syringe

Concentration
– mg/mL
Per 1 unit
– mcg
Draws per vial
–
Total in vial
– mcg
What each mark on the syringe holds
UnitsmLContains

About Retatrutide

Retatrutide is an investigational triple agonist of the GIP, GLP-1 and glucagon receptors. In the phase 3 TRIUMPH-1 trial, adults with obesity lost an average of 28.3% of body weight at the 12 mg dose over 80 weeks, according to topline results Lilly reported in May 2026.

Read the full Retatrutide profile

Retatrutide calculator questions

How much bacteriostatic water do I add to a 5 mg Retatrutide vial?

The calculator does not prescribe a volume; the right choice depends on how large you want each draw to be. As arithmetic: 5 mg in 2 mL gives 2.5 mg/mL, so each unit on a U-100 syringe holds 25 mcg. Use the “Water to add” tab to work backwards from a draw size.

What concentration does Retatrutide have after reconstitution?

Concentration is the vial mass divided by the water volume. For example, 5 mg in 2 mL is 2.5 mg/mL. Check the certificate of analysis for net peptide content, which is usually lower than the label.

Where can I read the research on Retatrutide?

See the Retatrutide research profile for mechanism, study findings, safety and regulatory status, with references.